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Precautions

It is critical that your medical professional look at progress at regular visits to allow for changes in your dose and to check for any negative effects.

Do not take selegiline if you have used meperidine (e.g., Demerol®) or perhaps an MAO inhibitor (MAOI) (e.g., isocarboxazid, phenelzine, tranylcypromine, Marplan®, Nardil®, or Parnate®) within the past 14 days. If you do, you could develop agitation, confusion, restlessness, stomach or intestinal symptoms, sudden high body temperature, very high blood pressure, or severe convulsions.

Do not take cough medicines (e.g., dextromethorphan, Robitussin®, Pediacare®) or pain medicines (e.g., methadone, propoxyphene, tramadol, Darvon®, Dolophine®, Ultram®) while you happen to be applying this medicine. Using these medicines together could cause uncomfortable side effects.

Selegiline may cause serious unwanted effects when used together with some antidepressants. Tell your doctor if you've used amitriptyline, doxepin, fluoxetine, fluvoxamine, nortriptyline, paroxetine, sertraline, Elavil®, Luvox®, Pamelor®, Paxil®, Prozac®, or Zoloft® within the past two weeks.

When selegiline is taken at doses of 10 mg or less each day for the treatments for Parkinson's disease, there won't be any restrictions on food or beverages consume or drink. However, the opportunity exists that dangerous reactions, for example sudden high blood pressure, may occur if doses above those used by Parkinson's disease are taken with certain foods, beverages, or other medicines. These foods, beverages, and medicines include:

• Foods which may have an increased tyramine content (most frequent in foods which might be aged or fermented to increase their flavor), like cheeses; fava or broad bean pods; yeast or meat extracts; smoked or pickled meat, poultry, or fish; fermented sausage (bologna, pepperoni, salami, summer sausage) and other fermented meat; sauerkraut; or any overripe fruit. If a list of simply because and beverages is not directed at you, ask your medical professional to supply one.
• Alcoholic beverages or alcohol-free or reduced-alcohol beer and wine.
• Large levels of caffeine-containing food or beverages for example coffee, tea, cola, or chocolate.
• Any other medicine unless approved or prescribed by your doctor. This especially includes nonprescription (over-the-counter [OTC]) medicine, like that for colds (including nose drops or sprays), cough, asthma, hay fever, and appetite control; “keep awake” products; or goods that cause you to sleepy.

Also, for about 14 days as soon as you stop using this medicine, these foods, beverages, along with other medicines may continue to react with selegiline whether or not this was taken in doses greater than those usually useful for Parkinson's disease.

Check with your physician or hospital emergency room immediately if severe headache, stiff neck, chest pains, fast heartbeat, or nausea and vomiting occur while you might be taking this medicine. These may be signs of a serious complication that will possess a doctor's attention.

Dizziness, lightheadedness, or fainting may occur, particularly when you receive up from the lying or sitting position. Getting up slowly may help. If the problem continues or gets worse, check with your physician.

Selegiline could cause dryness from the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice inside your mouth, or make use of a saliva substitute. However, should your mouth continues to feel dry in excess of 14 days, check along with your medical doctor or dentist. Continuing dryness in the mouth may increase the chance of dental disease, including cavities, gum disease, and fungus infections.

It is essential that your physician look at your skin for melanoma (tumor) regularly if you've got Parkinson's disease.

Do not stop using this medicine without first checking with your physician. Your doctor may want that you reduce gradually the amount you are taking before stopping completely.

Hallucinations may appear in some patients. This is more established with elderly patients. If you might have hallucinations, consult a medical expert.

Some individuals who have used this medicine had unusual changes in their behavior. Talk with a medical expert in the event you start having problems with gambling or increased libido while using this medicine.